Researchers at the Valencia University in conjunction with
the Health
Carlos
III
Institute of
Madrid
proposed
an alternative
on
interaction
between
HIV
and the
immune
system.
Where they can recognize the viral epitopes that are viral proteins in the infected cell surface and that these viruses mutate its genome to escape but in the case of HIV genome variability not to be expected.
Where they can recognize the viral epitopes that are viral proteins in the infected cell surface and that these viruses mutate its genome to escape but in the case of HIV genome variability not to be expected.
PLOS Biology researches, It
is
proposed
that
the fact that
the
virus
infects
cells that
belong to the
same immune
system T
helper lymphocytes.
And
that HIV
infects most
often the
active
cell
to
the sleepers,
and that these
are activated
when they
recognize an
epitope therefore
propose
that HIV does
not always
can´t
evade the immune
system, so they have
developed a
mathematical model of interactions on the network between the different types of cells and viruses.
As
there are two
versions on
the
speaking
of
viruses infect
immune
cells
and
infecting
other
cells
as in the case
of HIV,
and
that
this
depends on the
activation of
lymphocytes appear
to favor viral
epitopes
may
be
recognized by
the
immune
system.
With regard to the vaccine, the authors propose that the present vaccine epitopes to the immune system of the pathogens to be recognized and react to infection wing but in turn this could be counterproductive, but instead of this vaccine would be aimed only viral epitopes recognized by another type of lymphocytes as are cytotoxic, which are responsible for destroying the virus.
With regard to the vaccine, the authors propose that the present vaccine epitopes to the immune system of the pathogens to be recognized and react to infection wing but in turn this could be counterproductive, but instead of this vaccine would be aimed only viral epitopes recognized by another type of lymphocytes as are cytotoxic, which are responsible for destroying the virus.
Comments
The researchers
therefore
proposed
an interesting
method, as
change the
functionality and
most of all is
directed toward
the target
where
the vaccination
but
the
fact
generate
cytotoxic
lymphocyte
activation may
also
affect
other cells
that can
same
sites
present
antigenic
similarities and
destroy
not only the
virus,
so you
should
keep trying
other
alternatives which
should be
targeted
towards
the antigenic
variability that
is
more
constant in
the case of HIV
that by
activating the
immune
system itself.
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